Not known Factual Statements About Lenvatinib
phenobarbital will lower the extent or influence of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.levoketoconazole will boost the degree or result of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
To stop dehydration, it can be crucial to drink an abundance of fluids while you are currently being addressed with this particular drug. Speak to your physician or pharmacist When you've got any concerns.
Bortezomib is FDA-authorized to be used in the initial treatment of numerous myeloma together with cyclophosphamide and dexamethasone. It is usually FDA-approved to be used from the cure of various myeloma in people who Formerly responded to bortezomib and relapsed at the very least six months following the completion with the prior cure.
Folks making use of this medication could have significant side effects. However, you are actually prescribed this drug because your physician has judged which the gain for you is greater than the chance of Unwanted effects. Mindful monitoring by your physician may lower your threat.
ribociclib will raise the stage or influence of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
fosphenytoin will minimize the extent or outcome of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
cannabidiol will improve the amount or outcome of bortezomib by influencing hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Closely. Think about minimizing the dose of sensitive CYP2C19 substrates, as clinically proper, when coadministered with cannabidiol.
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atazanavir will boost the amount or influence of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
deferasirox will minimize the level or impact of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
The drug is metabolized with the CYP3A4 and CYP2C19 enzymes from the liver. The metabolites are Lp-PLA2-IN-1 inactive and are excreted because of the kidney.
verapamil will increase the level or impact of bortezomib Crenolanib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
bortezomib will improve the level or outcome of mavacamten by affecting hepatic enzyme CYP2C19 metabolism. Contraindicated. Potent or reasonable CYP2C19 inhibitors may raise mavacamten systemic exposure, leading to coronary heart failure due to systolic dysfunction.